Abstract Background Chemoradiotherapy (CRT) remains one of the most common cancer treatment modalities, and recent data suggest that CRT is maximally effective when there is generation of an anti-tumoral immune response.However, CRT has also been shown to promote immunosuppressive mechanisms which must be blocked or reversed to maximize its immune
Generation of skeletal muscles with forms adapted to their function is essential for normal movement.Muscle shape is patterned by the coordinated polarity of collectively migrating myoblasts.Constitutive inactivation of the protocadherin gene Fat1 uncoupled individual myoblast polarity within chains, altering the shape of selective groups of muscle
Abstract Background Hypertension plays a significant role in the global burden of cardiovascular diseases.The planned approach to community health (PATCH), as a community-based framework, highlights community participation in decision-making.This study aimed to determine the effectiveness of a community-based intervention using the PATCH on disease